StemRD LDN-193189 小分子工具 產(chǎn)品英文簡(jiǎn)述：
A selective inhibitor of bone morphogenetic protein （BMP） type I receptors （ALK-2 and ALK-3）. Only weakly inhibits ALK-4,-5, and -7.
4-[6-（4-Piperazin-1-yl-phenyl）-pyrazolo[1,5-a]pyrimidin-3-yl]-quinoline
Ref: Cuny, G.D., et al. Structure-activity relationship study of bone morphogenetic protein （BMP） signaling inhibitors. Bioorg Med Chem Lett 18: 4388-92, 2008.
Catalog # LDN-02; LDN-10; LDN-50 Description A selective inhibitor of bone morphogenetic protein (BMP) type I receptors (ALK-2 and ALK-3). Only weakly inhibits ALK-4, -5, and -7. 4-[6-(4-Piperazin-1-yl-phenyl)-pyrazolo[1,5-a]pyrim idin-3-yl]-quinoline Ref: Cuny, G.D., et al. Structure-activity relatio nship study of bone morphogenetic protein (BMP) signaling inhibitors. Bioorg Med Chem Lett 18: 4388-92, 2008. Formulation Powder Reconstitution Before reconstitution, we recommend a brief spin to drive down a ny material dislodged from the bottom of the tube. The compound is soluble in DMSO. Stability The powder is stable for at least 2 year if stored at -20 degree C. The dissolved compound is stable for at least 1 month at 4 degree C, but should be stored in aliquots at -20 degree C for longer term. Protect from light. Purity Greater than 98% as determined by LC/MS analysis. LC/MS a nd/or NMR data available upon request. Biological Activity Not determined. Structural Info MW: 406.48 Formula: C25H22N6 Solubility: Soluble in DMSO at 10 mM. CAS: 1062368-24-4 For Research Use Only. Not for Use in Humans.
? Purity: Greater than 98% as determined by LC/MS analysis.
? Biological Activity: Not Determined
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